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Cytiva™ superSEC resin is part of our Custom Designed Media program. It is an alternative to Sepharose™ CL-2B, which purifies exosomes at small scale. Cytiva™ superSEC resin is suitable for much higher flows, up to 300 cm/h at 20 cm bed height (<200 kPa).
- Efficient industrial-scale purification of large biomolecules based on our well-established platform of size exclusion chromatography (SEC) resins
- Flexible process design due to large operational window of flow rates and bed heights
- Shorter chromatography cycle time and, consequently, improved productivity compared with Sepharose CL-2B
- Excellent chemical stability
Cytiva™ superSEC resin is based on an agarose base matrix with good pressure-flow properties and relatively large porosity. The pore size distribution makes the resin suitable for fractionation of exosomes and similarly sized entities from smaller sized impurities, like host cell proteins and enzymatically degraded DNA. The features of the base matrix make Cytiva™ superSEC resin an excellent choice for high-productivity purification of large biomolecules. The hydrophilic nature of the resin minimizes nonspecific adsorption and maximizes recovery of the desired biomolecule or entity.
