收藏
询价
Biacore 8K+
Biacore™ 8K+ SPR system
Biacore 8K+ 是高灵敏度的 SPR 系统，以卓越的容量与通量著称，应用于高通量筛选、抗体筛选、表征分析、工艺优化和质量控制，提供用于筛选和相互作用表征分析的一体化解决方案。
产品规格
Biacore™ 8K+ SPR system
| Analysis temperature | 4°C to 40°C (maximum 20°C below ambient temperature) |
| Analysis time per cycle | Typically 2 to 15 min |
| Application | Kinetic and affinity data (ka, kd, KD), specificity, selectivity, and screening data, epitope binning, concentration and relative potency data |
| Association rate constant (ka) | Proteins: up to 109; M-1s-1; LMW molecules: up to 107 M-1s-1 |
| Automation | 72 h unattended operatio |
| Baseline drift | Typically < 0.3 RU/min |
| Baseline noise | Typically < 0.02 RU (RMS) |
| Capacity | 12 × 96- or 384-well microplates, normal and deep-well |
| Detection technology | Surface plasmon resonance (SPR) biosensor |
| Dissociation rate constant (kd) | 10-6 to 0.5 s-1 |
| Flow cell volume | 40 nL |
| Flow rate | 1 to 100 μL/min |
| In-line reference subtraction | Automatic |
| Includes | Biacore™ 8K+ instrument, waste container, 2x Biacore Insight Evaluation software licenses, 2x Extended Screening and Characterization licenses, table with wheels (1150 x 600 mm) |
| Injection volume | 1 to 200 µL |
| Instrument dimensions, W × H × D | 902 × 875 × 616 |
| Item description | High sensitivity SPR system with outstanding capacity for use in screening, characterization, process optimization, and quality control. |
| Mains requirement | Processing unit: Autorange voltage 100 to 240 V~, frequency 50/60 Hz |
| Molecular weight detection | No lower limit for organic molecules |
| Number of flow cells | 16 in 8 channels |
| Power consumption | Processing unit: max 550 VA |
| Refractive index | 1.33 to 1.39 |
| Sample concentration min. | ≥ 1 picomolar (pM) |
| Sample type | Small-molecule drug candidates to high-molecular weight proteins (also DNA, RNA, polysaccharides, lipids, cells, and viruses) in various sample environments (e.g., in DMSO-containing buffers, plasma, and serum) |
| Sample volume min. | Injection volume plus 20 to 50 μL (application dependent) |
| Weight | 141 kg |
产品详情
Biacore 8K+ 是高通量、高灵敏度的SPR 系统，能够以最大容量提供高质量的结合数据。Biacore 8K+ 旨在应对高通量筛选、抗体筛选、表征分析、工艺优化和质量控制方面的最严峻挑战。
Biacore 8K+产品优势：
- 用于相互作用分析的一体化解决方案，支持筛排、动力学、亲和力、浓度和相对效价分析。
- 每天筛选 2,300 个分子。
- 多达 12 × 384 孔微孔板的出色样品容量。
- 无人值守运行时间长达 72 小时，具有队列功能和快速多通道分析功能。
Biacore 8K+性能可满足最严苛的应用需求
Biacore 8K+ ——八进样针、高灵敏度 SPR 系统，能够对16 组样品进行相互作用检测，并快速提供动力学和亲和力数据。此高通量筛选系统可有效地缩短获得结果所需的时间，最短仅为单进样针系统的八分之一。两个系统均实现了仪器灵活性和通量的完美结合，可减少实验运行时间，即使对于复杂的靶标和新型药物如双特异性抗体也是如此。
Biacore 8K+系统为您提供用于筛选和相互作用表征分析的一体化解决方案，小到片段药物，大到多结构域蛋白样品，甚至是粗样品，都非常适合用此系统进行分析。
