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MabSelect SuRe 的重组蛋白 A 配基的设计可以耐受 0.1 – 0.5 M NaOH，从而可以高效清洁层析填料。
- In process-scale applications, this NaOH tolerance extends the lifetime of the resin and allows for the use of rigorous and cost-effective CIP and sanitization protocols.
- In research applications, this NaOH tolerance enables the purification of multiple antibody types with minimized cross-contamination risk.
- Protein ligand designed for enhanced protease resistance compared with unmodified protein A leads to lower ligand leakage.
- Meets industrial demands in terms of comprehensive technical and regulatory support and security of supply.
- Animal-component free raw materials and manufacturing process.
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MabSelect SuRe 填料特性
这种用于单克隆抗体 (mAb) 纯化的填料包含刚性、高流速琼脂糖基架，可提供优异的压力/流速特性。与 Cytiva 的许多蛋白 A 层析填料一样，MabSelect SuRe 使用定向配基偶联来实现优异的结合载量。它显示出较低的非特异性蛋白结合率，从而降低了洗脱组分中的杂质水平。
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