PreDictor™ RoboColumn™ Capto™ AVB

Prepacked minicolumns for high-throughput process development of adeno-associated virus (AAV) purification.

These PreDictor™ RoboColumn™ minicolumns for high-throughput process development are prepacked with Capto™ AVB affinity chromatography resin for AAV purification.

  • Supports high-throughput process development (HTPD) — enables parallel screening of chromatographic conditions using a miniaturized column format and robotic workstation.
  • Miniaturized column format — facilitates screening of a wide range of parameters with small sample consumption.
  • Reduced experimental time — automation and parallel screening minimize labor and save time.
  • Increased process understanding — high-throughput workflow allows investigation of enlarged experimental workspace for better process understanding.
  • Packed with Capto™ AVB resin — a BioProcess™ affinity resin for AAV purification.

PreDictor™ RoboColumn™ unit: a format suitable for HTPD

PreDictor™ RoboColumn™ units are prepacked, miniaturized columns that support HTPD using a robotic liquid handling workstation for fully automated and parallel chromatographic separations. HTPD work can be performed using PreDictor™ RoboColumn™ units alone, or as a complement to PreDictor™ 96-well filter plates.

PreDictor™ RoboColumn™ units can be operated in true chromatography mode, enabling dynamic binding capacity studies, while 96-well plates enable the study of static binding capacities.

PreDictor™ RoboColumn™ units are supplied in rows of eight columns with the same chromatography resin, and can be individually and easily arranged on an array plate containing 96 positions.

Read more about HTPD.

Capto™ AVB affinity chromatography resin

Capto™ AVB is an affinity resin designed for AAV purification. It is based on a rigid base matrix, delivering excellent pressure-flow properties for AAV viral vector production.

Capto™ AVB affinity resin is produced with reliable manufacturing procedures and can withstand standard cleaning-in-place (CIP) and sanitization procedures. As a BioProcess™ resin, this resin is supported by regulatory support files and comprehensive documentation, as well as security of supply services.

Learn more about Capto™ AVB resin.

RoboColumn is a trademark of Repligen GmbH.

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