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Cadence™ virus inactivation system

Cadence virus inactivation system (VI – Control system complete with two pH probes, CE version)
Single-use virus inactivation system for batch and continuous processing.

Air supply 6 barg (Main control unit feeds air to the mixers)
Dimensions main control unit 1100 x 900 x 2005 mm without warning light
Electricity supply Single phase
Manifold Gamma irradiation dose 25-50 kGy
Manifold Hose and connectors All tubing is silicone, with CPC connectors internally and sanitary clamp connectors to interface with upstream and downstream processes
Manifold Pressure PendoTECH pressure transmitter
Manifold Recirculation pump Insert is standard silicone tubing rated for 24 hours operation
Manifold Transfer pump Insert is standard silicone tubing rated for 24 hours operation
Manifold Tube size 1/4 in., 3/8 in., 1/2 in.
Max. operating pressure 0.4 barg single-use assembly (Atmospheric pressure only in mixer biocontainer)
Weight main control unit 350 kg (main control unit)
SKU: CADVISYS1CE 分类: ,

The Cadence™ Virus Inactivation (VI) system is a fully automated system that provides the ability to perform low pH virus inactivation to an incoming elution stream continuously, with minimal operator involvement.

  • Designed for integrated unit operation
  • Fully automated for true continuous processing
  • Reduced risk of operator error
  • Ability to operate in batch or continuous mode for flexible facility fit

The system will collect the elution stream from a continuous chromatography system. However, it can easily process as standalone system or with a batch chromatography system.

The system automates sequentially: eluate collection, pH decrease, hold at low pH, pH neutralization, and the transfer to the next unit operation.

The system comprises of a control unit which attaches to one or two system specific Allegro™ single-use mixers dependent on the application. The specification of the manifolds currently supports

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