Mustang™ Q and S chromatography membranes in XT Acrodisc™ capsule

Disposable membrane ion-exchange chromatography units for scale-down process development

Mustang™ XT Acrodisc™ units, available in Q and S chemistries, are suitable for scale-down process development work in a variety of downstream process applications.

  • Fast, easy-to-use, scale-down Mustang membrane unit facilitates process development work
  • Device volume of < 1 mL minimizes sample volume requirements
  • 16 layers of Mustang membrane allow easy scale-up to Mustang membrane pilot- and process-scale capsules
  • Units achieve flow rates of up to 10 membrane volumes per minute (MV) without affecting performance
  • Female Luer lock inlet and outlet simplifies use with typical low-pressure chromatography systems
  • Disposable 25 mm units.

Mustang Q Membrane

Mustang Q membrane is anion-exchange support with pendant quaternary amine functional groups in a cross-linked polymeric coating on a 0.8-micron pore-size membrane. This gives high dynamic capacities for high molecular weight products such as DNA, plasmids, or even particles as large as viruses.

Mustang S Membrane

Mustang S membrane is cation-exchange support with pendant sulfonic functional groups in a cross-linked polymeric coating on a 0.65 µm pore-size membrane. This gives high dynamic capacities for high molecular weight products such as IgG, Factor VIII, and some viruses.

Mustang XT Acrodisc units, available in Q and S chemistries, are ideal for scale-down process development work in a variety of downstream process applications. A membrane volume of < 1 mL reduces the amount of sample required for evaluation, and the female Luer lock inlet and outlet simplifies connection to typical low-pressure chromatography systems. The open-pore structure eliminates diffusion limitations of conventional macroporous sorbents, allowing biomolecules to access all binding sites by the convective flow. In addition, the large pores eliminate the size exclusion effect allowing full access to the binding chemistry for very large proteins, plasmids, and viruses.

超越重力:密度梯度分离介质的设计与实践

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