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Allegro™ Connect depth filtration system

Single-use automated filtration system designed to deliver robust process control during the clarification/harvest step.

The Allegro™ Connect Depth Filtration System is a single-use automated filtration system designed to deliver robust process control during the clarification/harvest step.

  • Automatically performs pre-use water flushing, product filtration and buffer chase – utilizing standard manifolds
  • Filters up to 2000 L* of process stream from a bioreactor scale
  • Supports a total of 30 m2 first stage, 20 m2 second stage installed filter chassis and up to 2 × 762 mm (30 in.) in-line bioburden reduction filters installed on the system cabinet to reduce footprint
  • Combined manifold and installed filter leak test to ensure a correctly assembled flow path with no leaks prior to application of process fluid
  • Electronic batch records (summary and detailed), compiling data from the single-use sensors within the flow path and other critical process parameters
  • Common automation software (Wonderware based) used across the Allegro Connect range, which aids ease of recipe creation and operator usability
  • A complete single-use flow path can be installed or uninstalled by a single operator in < 90 minutes

* Larger volumes may be possible for less challenging process streams

This next generation compact and elegant system is designed to minimize risk through a fully automated process with recipe-controlled steps, including pre-use manifold leak test, system priming, product filtration and buffer chase, with all data stored in a batch reporting system, significantly reducing non-conformities and manual labor.

New design features enable manifolds to be configured to meet various process needs; supporting different process trending sensors and a wide range of liquid filter capsules and filters.