Biacore™ 4000 表面等离子共振系统
Biacore 4000
Biacore™ 4000 已停产,并替换为 Biacore™ 8 系列。 将于 2024 年 8 月 31 日停止为 Biacore™ 4000 提供维护服务。在此之后,能否继续提供维护服务将取决于我们的供应商是否备有可用零件。
停产,可选替代产品
Biacore 8K
产品规格
Biacore 4000
Additional Packages | Antibody extension, LMW extension |
Affinity range | fM to mM |
Analysis temperature | 4°C to 40°C |
Application | Kinetics/affinity characterization, kinetics/affinity screening, LMW interaction analysis, fragment screening, epitope mapping, immunogenicity*, concentration analysis. |
Association Rate (ka) (proteins) | 103 to 109 M-1s-1 |
Baseline drift | < 0.3 RU/min in ambient temperature range 15°C to 35°C |
Baseline noise | < 0.1 RU (RMS) |
Concentration range | 2 pM to 2 mM |
Data Collection Rate | 1 or 10 Hz |
Data Evaluation Time | 120 curve sets < 6 min |
Detection technology | Surface plasmon resonance (SPR) biosensor |
Dissociation Rate (kd) | 5 × 10-5 to 1 s-1 |
Footnote | * The application can be performed with limitations in software and/or hardware functionality |
GxP Support | Yes (included) |
Immobilized Interactant Consumption | 3 – 10 µg per immobilized spot |
Immobilized Molecule Consumption | 3 to 10 μg/spot |
Includes | Biacore 4000 includes a processing unit, control and evaluation software, Windows operating system, barcode scanner and a dedicated trolley for the processing unit and thermostat unit. The computer and the external thermostat unit for reliable temperature control of sample compartment are ordered seperately. |
Molecular Weight Limit | > Mr 50 |
Number of flow cells | 4 × 5 spots |
Precision (concentration analysis) | <5% CV |
Sample Capacity | Antibodies: 10 × 96, LMW: 6 × 384 |
Sample storage temperature | 4°C to 40°C |
Sample Volume (kinetics) | 28 to 376 μL |
Unattended Run Time | 60 h |
产品详情
高通量 SPR 系统可提供高质量的相互作用数据,从而在抗体选择、药物发现等方面做出更明智的决策。
- 高灵敏度
- 60 小时无人值守运行,可并行多达分析 16 个靶点。
- 大规模分子分析在 24 小时内产生多达 4800 种相互作用。
- 创新软件解决方案可提高生产率和性能。
Biacore™ 4000 包括
主机、控制和分析软件、Windows 操作系统、条形码扫描仪以及用于主机和恒温器单元的专用推车。计算机和用于可靠控制样品室温度的外部恒温器单元需单独订购。