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Pegasus Protect membrane in Microdisc capsules

Protecting critical virus filtration

Pegasus™ Protect membrane in Microdisc capsules, a Pall Life Sciences product, are optimized for the confirmation and validation of performance at a small scale using minimal volumes of process fluid.

Pegasus Protect virus prefiltration combines with Pegasus Prime virus filtration to deliver the first gamma-sterilized pre-filter & virus filter combination. Together, these simplify process development, validation and operations while saving time and delivering improved process economy.

Process developers can quickly deliver a robust, scalable virus filtration process using a minimum of sample volume, and be confident of successful virus validation. This choice supports clinical manufacturing with a solution that is easy to use and versatile to work alone or with integrated and automated single-use systems.

Both gamma irradiated and non-irradiated Microdisc capsules containing Pegasus Protect media are optimized for the confirmation and validation of performance at a small scale using minimal volumes of process fluid.

Performance established during small scale trials can be easily scaled as both Pegasus Protect prefilters and Pegasus Prime virus filters are available in a range of optimized capsule and filter formats which maintain a constant area ratio between prefiltration and virus filtration at all scales.

All process scale devices can be integrated into single-use and automated solutions to offer the highest degree of control, flexibility and security.

Materials of Construction

Filter Membrane: Nylon
Housing, Vent Plug and Support: Polypropylene

Retention Ratings

Pore size : 0.2 μm nominal

Effective Filter Area (EFA) (Nominal)

3.9 cm2

Operating Parameters

Maximum Temperature: 40°C
Maximum Pressure: 3.1bar (45 psi)*
Maximum Differential Pressure: 3.1 bar (45 psi)*
*up to 12 hours at 25°C; up to 6 hours at 40°C

Recommended Operating Conditions

35 mbard (0.5 psid) or 2 mL/min water at 20°C*
*when used with Pegasus Prime Microdisc capsules

Typical Hold-Up Volume (with air purge)

< 125 μL

Dimensions (Nominal)

Length: 2.0 cm (0.8 in.)
Diameter : 3.0 cm (1.2 in.)

Connection Type

Female Luer-Lock inlet, male slip Luer outlet

 

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